LGALS13 抗体 (AA 23-134) (CF®568)
Quick Overview for LGALS13 抗体 (AA 23-134) (CF®568) (ABIN6189436)
抗原
See all LGALS13 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
 - AA 23-134
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原理
 - Mouse Monoclonal anti-Galectin-13 / Placental-Protein-13 (PP13/1162), CF568 Conjugate
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产品特性
 - This antibody recognizes a 32 kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble ?-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
 - Recombinant human Galectin-13 protein fragment (aa23-134) (exact sequence is proprietary)
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亚型
 - IgG2b
 
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应用备注
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                        Immunohistology (formalin) 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris, 1 mM EDTA pH 9.0 or 10 mM citrate buffer pH 6.0 for 10-20 min followed by cooling at RT for 20 min
 - Immunofluorescence 0.5-1 μg/mL
 - Flow Cytometry 0.5-1 μg/million cells/0.1 mL
 - ELISA For coating, order Ab without BSA
 - Optimal dilution for a specific application should be determined by user
 
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说明
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K-562 cells. Placenta or Spleen.
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 100 μg/mL
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缓冲液
 - PBS/0.1 % BSA/0.05 % azide
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Protect from light
 
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- LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))
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别名
 - Galectin-13 / Placental-Protein-13
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背景
 - Gal-13, GAL13, Galactoside-binding soluble lectin 13, Galectin-13, Galectin13, Lectin galactoside binding soluble 13, LGALS13, PLAC8, Placental protein 13 (PP13), Placental tissue protein 13
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分子量
 - 16 kDa (monomer), 32 kDa (homodimer)
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基因ID
 - 29124, 23671
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UniProt
 - Q9UHV8
 
抗原
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