LGALS13 抗体 (AA 23-134) (CF®405S)
Quick Overview for LGALS13 抗体 (AA 23-134) (CF®405S) (ABIN6189422)
抗原
See all LGALS13 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 23-134
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原理
- Mouse Monoclonal anti-Galectin-13 / Placental-Protein-13 (PP13/1162), CF405S Conjugate
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产品特性
- This antibody recognizes a 32 kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble ?-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human Galectin-13 protein fragment (aa23-134) (exact sequence is proprietary)
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亚型
- IgG2b
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应用备注
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Immunohistology (formalin) 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris, 1 mM EDTA pH 9.0 or 10 mM citrate buffer pH 6.0 for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- ELISA For coating, order Ab without BSA
- Optimal dilution for a specific application should be determined by user
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说明
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K-562 cells. Placenta or Spleen.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))
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别名
- Galectin-13 / Placental-Protein-13
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背景
- Gal-13, GAL13, Galactoside-binding soluble lectin 13, Galectin-13, Galectin13, Lectin galactoside binding soluble 13, LGALS13, PLAC8, Placental protein 13 (PP13), Placental tissue protein 13
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分子量
- 16 kDa (monomer), 32 kDa (homodimer)
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基因ID
- 29124, 23671
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UniProt
- Q9UHV8
抗原
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