PAX6 抗体 (N-Term)
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北京 101111
Quick Overview for PAX6 抗体 (N-Term) (ABIN6189117)
抗原
See all PAX6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-300, N-Term
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原理
- Mouse Monoclonal anti-PAX6 (PAX6/498), Purified, BSA-free
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产品特性
- Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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纯化方法
- Purified
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免疫原
- Recombinant fragment (N-terminus, aa 1-300) of human PAX6 protein
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亚型
- IgG1 kappa
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anti-Paired Box 6 (PAX6) (AA 1-122) antibody
PAX6 适用: 人 IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 1F6G2 unconjugated
anti-Paired Box 6 (PAX6) (AA 51-150) antibodyPAX6 适用: 人, 小鼠, 大鼠 FACS, ELISA, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 183-210) antibodyPAX6 适用: 人 WB, IF, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 352-380) antibodyPAX6 适用: 人 WB, IF, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 1-422) antibodyPAX6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 195-233), (Middle Region) antibodyPAX6 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 352-380) antibodyPAX6 适用: 人, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15517 unconjugated
anti-Paired Box 6 (PAX6) (AA 1-300) antibodyPAX6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 1-300) antibodyPAX6 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) antibodyPAX6 适用: 人 IHC 宿主: 小鼠 Monoclonal 706M unconjugated
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应用备注
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
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说明
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Pancreas or Cerebellum
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS (no BSA, no azide)
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储存液
- Azide free
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- PAX6 (Paired Box 6 (PAX6))
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别名
- PAX6
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背景
- AN2, Aniridia type II protein, Oculorhombin, Paired box gene 6 (aniridia keratitis), Paired box homeotic gene 6, Paired box protein Pax-6, Sey, WAGR
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分子量
- 47 kDa
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基因ID
- 5080, 611376
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UniProt
- P26367
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途径
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
抗原
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