TIMP3 抗体 (AA 175-211) (CF®488A)
Quick Overview for TIMP3 抗体 (AA 175-211) (CF®488A) (ABIN6188532)
抗原
See all TIMP3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 175-211
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原理
- Rabbit Polyclonal anti-TIMP3 CF488A Conjugate
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产品特性
- TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- The amino acid sequence (aa175-211), used as the immunogen for TIMP3 Ab, is 100% homologous in human, cow, dog and horse, and 94% homologous in mouse and rat.
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亚型
- IgG
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anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (Internal Region) antibody
TIMP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 151-211) antibodyTIMP3 适用: 人, 大鼠, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 26-211) antibodyTIMP3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 113-139) antibodyTIMP3 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21049 unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 170-188) antibodyTIMP3 适用: 人, Cow, 犬, 马, Pig, 绵羊, 猴 WB, IHC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 27-209) antibodyTIMP3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 119-148), (Middle Region) antibodyTIMP3 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 176-210), (C-Term) antibodyTIMP3 适用: 人 WB 宿主: 兔 Polyclonal RB47669 unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 1-184) antibodyTIMP3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 30-208) antibodyTIMP3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistology formalin-fixed 1-2 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
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说明
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Placenta or breast carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
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别名
- TIMP3
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背景
- HSMRK222, K222TA2, Protein MIG-5, SFD, Sorsby fundus dystrophy pseudo-inflammatory, TIMP metallopeptidase inhibitor 3, Tissue Inhibitor of Metalloproteinase 3
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分子量
- ~30 kDa
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基因ID
- 7078
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UniProt
- P35625
抗原
-
