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MYB 抗体 (AA 119-135) (Biotin)

This anti-MYB antibody is a 小鼠 单克隆 antibody detecting MYB in IF 和 FACS. Suitable for 人.
产品编号 ABIN6188387
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for MYB 抗体 (AA 119-135) (Biotin) (ABIN6188387)

抗原

See all MYB 抗体
MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

适用

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宿主

  • 106
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小鼠

克隆类型

  • 97
  • 34
单克隆

标记

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This MYB antibody is conjugated to Biotin

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

MYB286
  • 抗原表位

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    AA 119-135

    原理

    Mouse Monoclonal anti-c-Myb (MYB286), Biotin Conjugate

    产品特性

    The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb oncoprotein, coupled to KLH

    亚型

    IgG1 kappa
  • 应用备注

    Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user

    说明

    Jurkat, MOLT-4, COLO or BT-20 cells. Colon or breast carcinomas.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

    别名

    c-Myb

    背景

    C-myb_CDS, efg, ONCOGENE AMV, Oncogene MYB, Proto-oncogene c-Myb, Transcriptional activator Myb, v-myb avian myeloblastosis viral oncogene homolog

    分子量

    75 kDa

    基因ID

    4602, 606320

    UniProt

    P01104

    途径

    Chromatin Binding, Positive Regulation of Immune Effector Process
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