MYB 抗体 (AA 119-135) (CF®568)
Quick Overview for MYB 抗体 (AA 119-135) (CF®568) (ABIN6188372)
抗原
See all MYB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 119-135
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原理
- Mouse Monoclonal anti-c-Myb (MYB286), CF568 Conjugate
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产品特性
- The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb oncoprotein, coupled to KLH
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亚型
- IgG1 kappa
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anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (AA 281-294) antibody
Verified MYB 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (C-Term) antibodyMYB 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (AA 1-640) antibodyMYB 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (C-Term) antibodyMYB 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (pSer532) antibodyMYB 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (N-Term) antibodyMYB 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (N-Term) antibodyMYB 适用: 人, 小鼠, 大鼠, 犬, Cow, 非洲爪蟾, 小鸡 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (AA 305-558) antibodyMYB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (N-Term) antibodyMYB 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (AA 1-50) antibodyMYB 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
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说明
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Jurkat, MOLT-4, COLO or BT-20 cells. Colon or breast carcinomas.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
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别名
- c-Myb
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背景
- C-myb_CDS, efg, ONCOGENE AMV, Oncogene MYB, Proto-oncogene c-Myb, Transcriptional activator Myb, v-myb avian myeloblastosis viral oncogene homolog
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分子量
- 75 kDa
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基因ID
- 4602, 606320
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UniProt
- P01104
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途径
- Chromatin Binding, Positive Regulation of Immune Effector Process
抗原
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