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HIV-1 p24 抗体 (Biotin)

This anti-HIV-1 p24 antibody is a 小鼠 单克隆 antibody detecting HIV-1 p24 in ELISA, IF, ICC 和 Coat. Suitable for Human Immunodeficiency Virus (HIV).
产品编号 ABIN6186525
发货至: 中国

Quick Overview for HIV-1 p24 抗体 (Biotin) (ABIN6186525)

抗原

See all HIV-1 p24 抗体
HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))

适用

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Human Immunodeficiency Virus (HIV)

宿主

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小鼠

克隆类型

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单克隆

标记

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This HIV-1 p24 antibody is conjugated to Biotin

应用范围

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ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Coating (Coat)

克隆位点

P24-661
  • 原理

    Mouse Monoclonal anti-HIV p24 (p24/661), Biotin Conjugate

    产品特性

    Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4 T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant HIV-1 Gag p24 protein

    亚型

    IgG1 kappa
  • 应用备注

    Immunocytochemistry Acetone or paraformaldehyde fixed 0.5-1 μg/mL
    • Immunofluorescence 0.5-1 μg/mL
    • ELISA For coating, order Ab without BSA
    • Optimal dilution for a specific application should be determined by user

    说明

    HIV-1 infected cells or tissues.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))

    别名

    HIV p24

    物质类

    Viral Protein

    背景

    Capsid protein p24, Human immunodeficiency virus type 1 p24, HIV1gp1, HIV-1 Gag p24

    分子量

    24 kDa (mature), 55 kDa & 41 kDa (precursors)

    基因ID

    155348
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