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Transferrin Receptor 抗体 (AA 94-212) (CF®405S)

This anti-Transferrin Receptor antibody is a 小鼠 单克隆 antibody detecting Transferrin Receptor in FACS, WB, IHC, ELISA, IF 和 Coat. Suitable for 人.
产品编号 ABIN6185318
发货至: 中国

Quick Overview for Transferrin Receptor 抗体 (AA 94-212) (CF®405S) (ABIN6185318)

抗原

See all Transferrin Receptor (TFRC) 抗体
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Transferrin Receptor antibody is conjugated to CF®405S

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Coating (Coat)

克隆位点

TFRC-1817
  • 抗原表位

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    AA 94-212

    原理

    Mouse Monoclonal anti-CD71 / Transferrin Receptor (TFRC/1817), CF405S Conjugate

    产品特性

    This antibody recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human TFRC protein fragment (aa94-212) (exact sequence is proprietary)

    亚型

    IgG2b kappa
  • 应用备注

    Flow cytometry 0.5-1 μg/million cells in 0.1 mL
    • Immunohistology (formalin) 1-2 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris, 1 mM EDTA  pH 9.0 for 10-20 min followed by cooling at RT for 20 min
    • ELISA 2-4 μg/mL for coating (order Ab without BSA)
    • Immunofluorescence 1-2 μg/mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user

    说明

    PC3 cells. Human placenta or breast carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    别名

    CD71 / Transferrin Receptor

    背景

    Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR

    分子量

    85-95 kDa (monomer), 190 kDa (dimer)

    基因ID

    7037, 529618

    UniProt

    P02786

    途径

    Transition Metal Ion Homeostasis
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