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Transferrin Receptor 抗体 (CF®640R)

This anti-Transferrin Receptor antibody is a 小鼠 单克隆 antibody detecting Transferrin Receptor in FACS 和 IF. Suitable for 人.
产品编号 ABIN6185170
发货至: 中国

Quick Overview for Transferrin Receptor 抗体 (CF®640R) (ABIN6185170)

抗原

See all Transferrin Receptor (TFRC) 抗体
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

适用

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小鼠

克隆类型

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单克隆

标记

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This Transferrin Receptor antibody is conjugated to CF®640R

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

66IG10
  • 原理

    Mouse Monoclonal anti-CD71 (66IG10), CF640R Conjugate

    产品特性

    This antibody recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Human thymocytes (T-cells)

    亚型

    IgG1 kappa
  • 应用备注

    Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user

    说明

    CCRF-CEM, Jurkat or K-562. Human placenta or breast carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    别名

    CD71

    背景

    Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR

    分子量

    85-95 kDa (monomer), 190 kDa (dimer)

    基因ID

    7037, 529618

    UniProt

    P02786

    途径

    Transition Metal Ion Homeostasis
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