L1CAM 抗体 (CF®405S)
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- 抗原 See all L1CAM 抗体
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This L1CAM antibody is conjugated to CF®405S
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF)
- 原理
- Mouse Monoclonal anti-CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF405S Conjugate
- 产品特性
- This antibody recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius), 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs), and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- Homogenous suspension of 16 week human fetal brain
- 克隆位点
- UJ127
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product L1CAM Primary Antibody
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- 应用备注
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Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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Neuroblastomas or Schwannomas
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
- 别名
- CD171 / L1CAM (L1 Cell Adhesion Molecule) (L1CAM 产品)
- 别名
- l1cam-a antibody, CAML1 antibody, CD171 antibody, HSAS antibody, HSAS1 antibody, MASA antibody, MIC5 antibody, N-CAM-L1 antibody, N-CAML1 antibody, NCAM-L1 antibody, S10 antibody, SPG1 antibody, L1 antibody, Hsas antibody, Hyd antibody, NCAML1 antibody, L1 cell adhesion molecule S homeolog antibody, L1 cell adhesion molecule antibody, l1cam.S antibody, L1CAM antibody, L1cam antibody
- 背景
- CAML1, HSAS1, Hyd, L1 Cell Adhesion Molecule, L1-NCAM, MASA, MIC5, NCAM-L1, Nerve-growth factor-inducible large external glycoprotein, Neural cell adhesion molecule L1, NILE, S10, SPG1
- 分子量
- 220-240 kDa
- 基因ID
- 3897, 52818
- UniProt
- P32004
- 途径
- Synaptic Membrane
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