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CD147 抗体 (CF®488A)

This CF®488A-conjugated 小鼠 单克隆 anti-CD147 antibody (Clone 8D6) specifically detects CD147 in FACS, IF, IHC (f) 和 AGG. The antibody is reactive with 人 samples.
产品编号 ABIN6183250
发货至: 中国
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Quick Overview for CD147 抗体 (CF®488A) (ABIN6183250)

抗原

See all CD147 (BSG) 抗体
CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

适用

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宿主

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小鼠

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单克隆

标记

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This CD147 antibody is conjugated to CF®488A

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Aggregation (AGG)

克隆位点

8D6
  • 原理

    Mouse Monoclonal anti-CD147 (8D6), CF488A Conjugate

    产品特性

    This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Human T cell line Molt 13

    亚型

    IgG1
  • 应用备注

    Immunohistology formalin-fixed 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1:100-1:200
    • Inhibits homotypic aggregation, adhesion to matrix, and migation thro ugh matrigel, order Ab without BSA/azide
    • Optimal dilution for a specific application should be determined by user

    说明

    HSB2 cells. Renal Cell, Ovarian carcinoma or Melanoma

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

    别名

    CD147

    分子量

    35 kDa (non-reduced), 40 kDa (reduced)

    基因ID

    682, 501293

    UniProt

    P35613

    途径

    S100 Proteins
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