CD147 抗体 (CF®647)
Quick Overview for CD147 抗体 (CF®647) (ABIN6183236)
抗原
See all CD147 (BSG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
 - Mouse Monoclonal anti-CD147 (8D6), CF647 Conjugate
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产品特性
 - This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
 - Human T cell line Molt 13
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亚型
 - IgG1
 
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应用备注
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                        Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
 - Flow Cytometry 0.5-1 μg/million cells/0.1 mL
 - Immunofluorescence 1:100-1:200
 - Inhibits homotypic aggregation, adhesion to matrix, and migation thro ugh matrigel, order Ab without BSA/azide
 - Optimal dilution for a specific application should be determined by user
 
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说明
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HSB2 cells. Renal Cell, Ovarian carcinoma or Melanoma
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 100 μg/mL
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缓冲液
 - PBS/0.1 % BSA/0.05 % azide
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Protect from light
 
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- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
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别名
 - CD147
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分子量
 - 35 kDa (non-reduced), 40 kDa (reduced)
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基因ID
 - 682, 501293
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UniProt
 - P35613
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途径
 - S100 Proteins
 
抗原
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