Cadherin-16 抗体
Quick Overview for Cadherin-16 抗体 (ABIN6182923)
抗原
See all Cadherin-16 (CDH16) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-Ksp-Cadherin / CDH16 (CDH16/1071), Purified, BSA-free
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产品特性
- This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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纯化方法
- Purified
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免疫原
- Recombinant human CDH16 protein
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亚型
- IgG1 kappa
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anti-Cadherin-16 (CDH16) (AA 37-287) antibody
CDH16 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin-16 (CDH16) (AA 353-617) antibodyCDH16 适用: 小鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Cadherin-16 (CDH16) antibodyCDH16 适用: 人 WB, FACS, IHC (f) 宿主: 兔 Monoclonal CDH16-1532R unconjugated Recombinant Antibody
anti-Cadherin-16 (CDH16) (AA 19-230) antibodyCDH16 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin-16 (CDH16) (AA 371-507) antibodyCDH16 适用: 人 WB, ELISA, IHC (f), Coat 宿主: 小鼠 Monoclonal CDH16-2125 unconjugated
anti-Cadherin-16 (CDH16) (AA 371-507) antibodyCDH16 适用: 人 ELISA, IHC (f), Coat 宿主: 小鼠 Monoclonal CDH16-2448 unconjugated
anti-Cadherin-16 (CDH16) antibodyCDH16 适用: 人 WB, FACS, IHC (f) 宿主: 小鼠 Monoclonal rCDH16-1071 unconjugated Recombinant Antibody
anti-Cadherin-16 (CDH16) (AA 1-829) antibodyCDH16 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Cadherin-16 (CDH16) antibodyCDH16 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-516R unconjugated Recombinant Antibody
anti-Cadherin-16 (CDH16) (C-Term) antibodyCDH16 适用: 人 IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
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说明
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Normal kidney or renal cell carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS (no BSA, no azide)
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储存液
- Azide free
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- Cadherin-16 (CDH16)
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别名
- Ksp-Cadherin / CDH16
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背景
- Cadherin-16 (CDH16), Kidney-specific cadherin, Ksp-cadherin antibody
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分子量
- 130 kDa
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基因ID
- 1014, 513660
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UniProt
- O75309
抗原
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