CD1a 抗体 (CF®488A)
Quick Overview for CD1a 抗体 (CF®488A) (ABIN6182604)
抗原
See all CD1a 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-CD1a (66IIC7), CF488A Conjugate
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产品特性
- At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Human thymocytes
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亚型
- IgG2a kappa
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anti-CD1a (CD1a) antibody
CD1a 适用: 人 IHC, WB, ELISA, ICC 宿主: 小鼠 Monoclonal 7A7 unconjugated
anti-CD1a (CD1a) (AA 151-250) antibodyCD1a 适用: 人 FACS, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-CD1a (CD1a) antibodyCD1a 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rC1A-711 unconjugated Recombinant Antibody
anti-CD1a (CD1a) antibody (FITC)CD1a 适用: 人 FACS 宿主: 小鼠 Monoclonal HI149 FITC
anti-CD1a (CD1a) antibody (APC)CD1a 适用: 人 FACS 宿主: 小鼠 Monoclonal HI149 APC
anti-CD1a (CD1a) antibody (PE)CD1a 适用: 人 FACS 宿主: 小鼠 Monoclonal HI149 PE
anti-CD1a (CD1a) (AA 1-311) antibodyCD1a 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal M1-2-1B5 unconjugated
anti-CD1a (CD1a) antibodyCD1a 适用: 人, 猕猴 FACS, IF, IHC, WB, StM 宿主: 小鼠 Monoclonal O10 unconjugated
anti-CD1a (CD1a) antibodyCD1a 适用: 人 IHC, StM 宿主: 兔 Monoclonal C1A-1506R unconjugated Recombinant Antibody
anti-CD1a (CD1a) antibodyCD1a 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-001M unconjugated Recombinant Antibody
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应用备注
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Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
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说明
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MOLT-4 cells. Paracortex in a tonsil or a reactive lymph node.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- CD1a
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别名
- CD1a
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背景
- Cortical thymocyte antigen CD1A, Epidermal dendritic cell marker CD1a, FCB6, HTA1, T cell surface antigen T6 / Leu 6, T-Cell Surface Glycoprotein CD1A
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分子量
- 49 kDa
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基因ID
- 909, 1309
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UniProt
- P06126
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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