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CD22 抗体 (CF®640R)

This anti-CD22 antibody is a 小鼠 单克隆 antibody detecting CD22 in FACS 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6181978
发货至: 中国

Quick Overview for CD22 抗体 (CF®640R) (ABIN6181978)

抗原

See all CD22 抗体
CD22 (CD22 Molecule (CD22))

适用

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人, 小鼠, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD22 antibody is conjugated to CF®640R

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

Myg13
  • 原理

    Mouse Monoclonal anti-CD22 (Myg13), CF640R Conjugate

    产品特性

    This antibody recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD . It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Human Raji cells

    亚型

    IgG1 kappa
  • 应用备注

    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user

    说明

    Raji, Daudi, IM9, JY25 and human peripheral blood lymphocytes. Human tonsil and lymphocytes.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    CD22 (CD22 Molecule (CD22))

    别名

    CD22

    分子量

    130-140 kDa

    基因ID

    933, 579691

    UniProt

    P20273
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