UGT1A9 抗体 (CF®568)
Quick Overview for UGT1A9 抗体 (CF®568) (ABIN6180734)
抗原
See all UGT1A9 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-UGT1A9 (UDP glucuronosyltransferase-1 family, polypeptide A9) (UGT1A9/1229), CF568 Conjugate
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产品特性
- This antibody recognizes a protein of about 60 kDa, which is identified as human UGT1A9. It does not cross-react with the other UGT1A isoforms including UGT1A7, UGT1A8, and UGT1A10 and shows a high degree of specificity. UGT1A9 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This MAb binds to human hepatocytes and the majority of human hepatocellular carcinomas (HCC s). In frozen sections, it stains hepatic cells and may be used as a marker of the liver. This MAb also binds to cell preparations of hepatocellular carcinoma biopsies or cell lines. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- A synthetic peptide specific to human UGT1A9 protein
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亚型
- IgG2b kappa
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应用备注
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
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说明
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HepG2 cells. Liver or Hepatocellular Carcinoma (HCC)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- UGT1A9 (UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))
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别名
- UGT1A9 (UDP glucuronosyltransferase-1 family, polypeptide A9)
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背景
- GNT1, HLUGP4, lugP4, UDP-glucuronosyltransferase 1-I, UDP-glucuronosyltransferase 1A9 (UGT1A9), UDPGT 1-9, UDPGT, UGT-1I, UGT1*9, UGT1-09, UGT1.9, Ugt1a9, UGT1I
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分子量
- 60 kDa
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基因ID
- 54600, 554822
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UniProt
- O60656
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途径
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
抗原
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