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TGF-beta 抗体 (CF®647)

TGFb 适用: 人, 小鼠, 大鼠, Cow, 犬, Hamster, 猴 Neut, Func 宿主: 小鼠 Monoclonal 1D11-16-8 CF®647
产品编号 ABIN6180690
发货至: 中国
  • 抗原 See all TGF-beta (TGFb) 抗体
    TGF-beta (TGFb)
    适用
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    人, 小鼠, 大鼠, Cow, 犬, Hamster, 猴
    宿主
    • 18
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    • 1
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    小鼠
    克隆类型
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    单克隆
    标记
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    This TGF-beta antibody is conjugated to CF®647
    应用范围
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    • 18
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    Neutralization (Neut), Functional Studies (Func)
    原理
    Mouse Monoclonal anti-TGF-beta (1D11.16.8), CF647 Conjugate
    产品特性
    This MAb recognizes TGF beta 1, 2 and 3. Three TGF? ?s have been identified in mammals. TGF? ?1, TGF? ?2 and TGF? ?3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF? ? requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGF? ?3 protein has approximately 80 % identity to the mature region of both TGF? ?1 and TGF? ?2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity. TGF? ?'s inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. See the < a href="https://biotium.com/wp-content/uploads/2013/07/CF-dye-selection-guide.pdf" target="_blank" rel="noopener">CF® Dye Selection Guide for more information. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Bovine TGF-beta2 protein
    克隆位点
    1D11-16-8
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TGFb Primary Antibody
  • 应用备注
    Cytokine neutralization or functional assay, order Ab without BSA/azideOptimal dilution for a specific application should be determined by user
    说明

    Salivary gland carcinoma

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    TGF-beta (TGFb)
    别名
    TGF-beta (TGFb 产品)
    别名
    CED antibody, DPD1 antibody, LAP antibody, TGFB antibody, TGFbeta antibody, TGF-beta antibody, TGF-BETA-1 antibody, TGF-beta1 antibody, TGFbeta1 antibody, Tgfb antibody, Tgfb-1 antibody, transforming growth factor beta 1 antibody, transforming growth factor beta-1 antibody, transforming growth factor, beta 1 antibody, TGFB1 antibody, Tgfb1 antibody
    背景
    GP40, Leu9, p41, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41
    分子量
    ~13 kDa
    基因ID
    7040, 7042, 7043
    途径
    EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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