TGF-beta 抗体 (CF®647)
Quick Overview for TGF-beta 抗体 (CF®647) (ABIN6180690)
抗原
See all TGF-beta (TGFb) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-TGF-beta (1D11.16.8), CF647 Conjugate
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产品特性
- This MAb recognizes TGF beta 1, 2 and 3. Three TGF? ?s have been identified in mammals. TGF? ?1, TGF? ?2 and TGF? ?3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF? ? requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGF? ?3 protein has approximately 80 % identity to the mature region of both TGF? ?1 and TGF? ?2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity. TGF? ?'s inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. See the < a href="https://biotium.com/wp-content/uploads/2013/07/CF-dye-selection-guide.pdf" target="_blank" rel="noopener">CF® Dye Selection Guide for more information. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Bovine TGF-beta2 protein
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亚型
- IgG1 kappa
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anti-TGF-beta (TGFb) (AA 301-350) antibody
TGFb 适用: 人, 小鼠, 大鼠, 兔, 绵羊 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta (TGFb) antibodyTGFb 适用: 人, 小鼠, 大鼠, Cow, 兔, 绵羊, Mink, Mustelid WB, ELISA, FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal TB21 unconjugated
anti-TGF-beta (TGFb) antibodyTGFb 适用: 人, 小鼠, 大鼠, 兔, 哺乳动物 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta (TGFb) antibodyTGFb 适用: 人, 小鼠, 大鼠, Cow, 犬, Hamster, 猴 ELISA, Func, D, ELISA (Capture) 宿主: 小鼠 Monoclonal TGFB-510 unconjugated
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应用备注
- Cytokine neutralization or functional assay, order Ab without BSA/azideOptimal dilution for a specific application should be determined by user
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说明
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Salivary gland carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- TGF-beta (TGFb)
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别名
- TGF-beta
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背景
- GP40, Leu9, p41, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41
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分子量
- ~13 kDa
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基因ID
- 7040, 7042, 7043
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途径
- EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
抗原
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