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P-Cadherin 抗体 (Biotin)

This anti-P-Cadherin antibody is a 小鼠 单克隆 antibody detecting P-Cadherin in WB, IF 和 FACS. Suitable for 人.
产品编号 ABIN6180179
发货至: 中国

Quick Overview for P-Cadherin 抗体 (Biotin) (ABIN6180179)

抗原

See all P-Cadherin (CDH3) 抗体
P-Cadherin (CDH3)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This P-Cadherin antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

12H6
  • 原理

    Mouse Monoclonal anti-P-Cadherin (12H6), Biotin Conjugate

    产品特性

    This antibody recognizes a protein of 116 kDa, identified as P-Cadherin-1 (CDH3). It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human full-length P-cadherin fusion protein

    亚型

    IgG1 kappa
  • 应用备注

    Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user

    说明

    A431 or PC-3 cells. Pancreas, Placenta or Prostate

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    P-Cadherin (CDH3)

    别名

    P-Cadherin

    背景

    Cadherin 3 type 1, Cadherin-3, Cadp, Calcium dependent adhesion protein placental, CDH3, CDHP, HJMD, P-cadherin (Placental), PCAD, Placental cadherin

    分子量

    116 kDa

    基因ID

    1001, 191842

    UniProt

    P22223
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