FSHR 抗体 (CF®405S)
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- 抗原 See all FSHR 抗体
- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FSHR antibody is conjugated to CF®405S
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- 原理
- Mouse Monoclonal anti-FSH Receptor (FSHR/1400), CF405S Conjugate
- 产品特性
- Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its ? and ? subunits. While the ? subunit of FSH is involved in the binding of FSH to the receptor, the ? subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome, a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- Recombinant human full-length FSHR protein
- 克隆位点
- FSHR-1400
- 亚型
- IgG1
- Top Product
- Discover our top product FSHR Primary Antibody
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- 应用备注
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Immunohistology (formalin) 1-2 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA
- pH 9.0
- or 10 mM citrate buffer
- pH 6.0
- for 10-20 min followed by cooling at RT for 20 min
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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Uterine Carcinoma
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
- 别名
- FSH Receptor (FSHR 产品)
- 别名
- FSHRO antibody, LGR1 antibody, ODG1 antibody, FSH-R antibody, eFSHR antibody, FSHRE antibody, fshr antibody, FSHR antibody, fshr-A antibody, GTHR-I antibody, zfGTHR-I antibody, LOC100304505 antibody, follicle stimulating hormone receptor antibody, follicle stimulating hormone receptor L homeolog antibody, follicle-stimulating hormone receptor antibody, FSHR antibody, fshr antibody, Fshr antibody, fshr.L antibody, Bm1_17785 antibody, LOC100304505 antibody
- 背景
- Follicle-stimulating hormone receptor, Follitropin receptor, FSH receptor, FSH-R, FSHRO, LGR1, ODG1, ovarian dysgenesis 1
- 分子量
- 75 kDa
- 基因ID
- 2492, 1428
- UniProt
- P23945
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling
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