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CD79a 抗体 (AA 202-216)

This anti-CD79a antibody is a 小鼠 单克隆 antibody detecting CD79a in FACS, IF 和 WB. Suitable for 人.
产品编号 ABIN6177639
发货至: 中国

Quick Overview for CD79a 抗体 (AA 202-216) (ABIN6177639)

抗原

See all CD79a (CD79A) 抗体
CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD79a antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)

克隆位点

IGA-1406
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    AA 202-216

    原理

    Mouse Monoclonal anti-CD79a (IGA/1406), Purified, with BSA

    产品特性

    A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    纯化方法

    Purified

    免疫原

    A synthetic peptide corresponding to aa 202-216 (GTYQDVGSLNIADVQ) of human CD79a protein.

    亚型

    IgG3
  • 应用备注

    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user

    说明

    Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    200 μg/mL

    缓冲液

    PBS/0.05 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

    别名

    CD79a

    分子量

    25-44 kDa

    基因ID

    973

    途径

    BCR Signaling
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