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RBP1 抗体

This anti-RBP1 antibody is a 小鼠 单克隆 antibody detecting RBP1 in IF 和 IHC (f). Suitable for 人, 小鼠, 大鼠, 兔, 猴, 山羊 和 Chimpanzee.
产品编号 ABIN6172701
发货至: 中国

Quick Overview for RBP1 抗体 (ABIN6172701)

抗原

See all RBP1 抗体
RBP1 (Retinol Binding Protein 1, Cellular (RBP1))

适用

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人, 小鼠, 大鼠, 兔, 猴, 山羊, Chimpanzee

宿主

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小鼠

克隆类型

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单克隆

标记

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This RBP1 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

G4E4
  • 原理

    Mouse Monoclonal anti-Retinol Binding Protein 1 (G4E4), Purified, BSA-free

    产品特性

    This MAb recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    纯化方法

    Purified

    免疫原

    Retinol binding protein-1 purified from human plasma

    亚型

    IgG1 kappa
  • 应用备注

    Immunohistology formalin-fixed 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user

    说明

    Hepatic or ovarian carcinoma

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS (no BSA, no azide)

    储存液

    Azide free
  • 抗原

    RBP1 (Retinol Binding Protein 1, Cellular (RBP1))

    别名

    Retinol Binding Protein 1

    分子量

    21-25 kDa

    基因ID

    5947, 5948, 5950

    UniProt

    P02753
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