FLI1 抗体 (AA 107-261) (Biotin)
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- 抗原 See all FLI1 抗体
- FLI1 (Friend Leukemia Virus Integration 1 (FLI1))
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抗原表位
- AA 107-261
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FLI1 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- 原理
- Mouse Monoclonal anti-FLI1 (FLI1/1312), Biotin Conjugate
- 产品特性
- This antibody recognizes a protein of 51 kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus.Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90 % of Ewing s Sarcoma (EWS)/Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11,22)(q24,q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi s Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- Recombinant fragment (aa 107-261) of human FLI1 protein (exact sequence is proprietary)
- 克隆位点
- FLI1-1312
- 亚型
- IgG
- Top Product
- Discover our top product FLI1 Primary Antibody
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anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 303-452) antibody
FLI1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4F2A9 unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 1-452) antibodyFLI1 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 205-331) antibodyFLI1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 1-452) antibodyFLI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G8 unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 54-73), (N-Term) antibodyFLI1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (N-Term) antibodyFLI1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (Internal Region) antibodyFLI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (Internal Region) antibodyFLI1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (AA 1-196) antibodyFLI1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Friend Leukemia Virus Integration 1 (FLI1) (Internal Region) antibodyFLI1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blotting 1-2 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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THP1 and Raji cells. Tonsil, Ewing s sarcoma (EWS) and Angiosarcoma
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- 抗原
- FLI1 (Friend Leukemia Virus Integration 1 (FLI1))
- 别名
- FLI1 (FLI1 产品)
- 别名
- EWSR2 antibody, SIC-1 antibody, FLI1 antibody, fli antibody, Xfli antibody, fli1 antibody, Xfli1 antibody, fli-1 antibody, Xfli-1 antibody, MGC121593 antibody, Fli-1 antibody, Sic1 antibody, cb855 antibody, wu:fc45b11 antibody, xlfli antibody, Fli-1 proto-oncogene, ETS transcription factor antibody, Fli-1 proto-oncogene, ETS transcription factor S homeolog antibody, Friend leukemia integration 1 antibody, Fli-1 proto-oncogene, ETS transcription factor a antibody, Fli-1 proto-oncogene, ETS transcription factor L homeolog antibody, FLI1 antibody, Fli1 antibody, fli1.S antibody, fli1 antibody, fli1a antibody, fli1.L antibody
- 分子量
- 51 kDa
- 基因ID
- 2313, 504281
- UniProt
- Q01543
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