FSHB 抗体 (CF®640R)
Quick Overview for FSHB 抗体 (CF®640R) (ABIN6170806)
抗原
See all FSHB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
 - Mouse Monoclonal anti-FSH-beta (FSHb/1062), CF640R Conjugate
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产品特性
 - This MAb reacts with a protein of 22 kDa, identified as beta sub-unit of FSH. It does not cross react with the alpha sub-unit. Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
 - Recombinant hFSH beta sub-unit
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亚型
 - IgG1 kappa
 
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应用备注
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                        Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
 - Flow Cytometry 0.5-1 μg/million cells/0.1 mL
 - Immunofluorescence 1-2 μg/mL
 - Optimal dilution for a specific application should be determined by user
 
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说明
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Anterior Pituitary
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 100 μg/mL
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缓冲液
 - PBS/0.1 % BSA/0.05 % azide
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Protect from light
 
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- FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))
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别名
 - FSH-beta
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背景
 - Follicle stimulating hormone beta polypeptide, Follicle stimulating hormone beta subunit, Follitropin beta chain, Follitropin subunit beta, FSH-B, FSH-beta, FSHB, FSHbeta
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分子量
 - 22 kDa
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基因ID
 - 2488, 36975
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UniProt
 - P01225
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途径
 - Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process
 
抗原
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