Thyroglobulin 抗体 (CF®647)
Quick Overview for Thyroglobulin 抗体 (CF®647) (ABIN6167863)
抗原
See all Thyroglobulin (TG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-Thyroglobulin (2H11 + 6E1), CF647 Conjugate
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产品特性
- Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Human thyroid follicular cells
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亚型
- IgG
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anti-Thyroglobulin (TG) (AA 2659-2768) antibody
TG 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal r6E1 unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) antibodyTG 适用: 人, 小鼠, 大鼠 IHC, StM 宿主: 小鼠 Monoclonal r2H11 unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-189R unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) (AA 2083-2333) antibodyTG 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 人, Cow IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC, StM 宿主: 兔 Monoclonal TGB-1970R unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Thyroglobulin (TG) (C-Term) antibodyTG 适用: 人 IHC (p) 宿主: 兔 Monoclonal E23-Y unconjugated
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应用备注
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Immunohistology formalin-fixed 0.1-0.2 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1.0 μg/million cells in 0.1 mL
- Optimal dilution for a specific application should be determined by user
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说明
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Thyroid
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- Thyroglobulin (TG)
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别名
- Thyroglobulin
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背景
- AITD3, hTG, TDH3, Tg, Tgn
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分子量
- 660 kDa (Dimeric Form)
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基因ID
- 7038, 654591
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UniProt
- P01266
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途径
- Thyroid Hormone Synthesis
抗原
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