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Plakophilin 1 抗体 (N-Term) (CF®568)

This CF®568-conjugated 小鼠 单克隆 anti-Plakophilin 1 antibody (Clone 10B2) specifically detects Plakophilin 1 in WB, IF 和 FACS. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN6166957
发货至: 中国
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Quick Overview for Plakophilin 1 抗体 (N-Term) (CF®568) (ABIN6166957)

抗原

See all Plakophilin 1 (PKP1) 抗体
Plakophilin 1 (PKP1)

适用

  • 21
  • 15
  • 1
  • 1
人, 小鼠

宿主

  • 16
  • 7
  • 1
小鼠

克隆类型

  • 15
  • 9
单克隆

标记

  • 17
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Plakophilin 1 antibody is conjugated to CF®568

应用范围

  • 23
  • 12
  • 9
  • 7
  • 6
  • 5
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

10B2
  • 抗原表位

    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term

    原理

    Mouse Monoclonal anti-Plakophilin-1 (10B2), CF568 Conjugate

    产品特性

    This antibody recognizes a protein of 75 kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    N-terminus of human Plakophilin-1 protein (exact sequence is proprietary)

    亚型

    IgG1
  • 应用备注

    Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user

    说明

    HaCat Cells.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    Plakophilin 1 (PKP1)

    别名

    Plakophilin-1

    背景

    B6P, B, 6 protein, PKP1, Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome)

    分子量

    75 kDa

    基因ID

    5317, 497350

    UniProt

    Q13835
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