PTH 抗体 (C-Term) (CF®647)
Quick Overview for PTH 抗体 (C-Term) (CF®647) (ABIN6166571)
抗原
See all PTH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- Mouse Monoclonal anti-PTH (Parathyroid Hormone) (N-&-C-Terminal) (3H9 + PTH/1175), CF647 Conjugate
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产品特性
- The epitope of this MAb maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2 levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Synthetic peptide corresponding to amino acids 1 to 34 of PTH conjugated to a carrier (3H9), Recombinant fragment (84 amino acid residues from C-terminus) of human PTH protein
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亚型
- IgG2b kappa
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anti-Parathyroid Hormone (PTH) antibody
PTH 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 人 IHC, StM 宿主: 兔 Monoclonal PTH-2295R unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 1-34) antibodyPTH 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-525R unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 人 IHC, WB, IHC (p) 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Parathyroid Hormone (PTH) antibodyPTH 适用: 人 IHC, IHC (p), HIER 宿主: 小鼠 Monoclonal 105G7 unconjugated
anti-Parathyroid Hormone (PTH) (AA 1-34) antibodyPTH 适用: 人 IHC, StM 宿主: 兔 Monoclonal PTH-1717R unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 1-34) antibodyPTH 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rPTH-911 unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 71-115) antibodyPTH 适用: 人 IHC, ELISA, IHC (p) 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Immunohistology (formalin)
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
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说明
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Human parathyroid gland carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- PTH (Parathyroid Hormone (PTH))
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别名
- PTH
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物质类
- Hormone
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背景
- HPTH, Parathormone, Parathyrin, Parathyroid hormone 1 (PTH1), Parathyroid hormone (PTH)
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分子量
- 9 kDa
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基因ID
- 5741, 37045
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UniProt
- P01270
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途径
- cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
-
