电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

S100A9 抗体 (CF®568)

This anti-S100A9 antibody is a 小鼠 单克隆 antibody detecting S100A9 in IF, FACS 和 IHC (f). Suitable for 人 和 大鼠.
产品编号 ABIN6161333
发货至: 中国

Quick Overview for S100A9 抗体 (CF®568) (ABIN6161333)

抗原

See all S100A9 抗体
S100A9 (S100 Calcium Binding Protein A9 (S100A9))

适用

  • 121
  • 24
  • 22
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
人, 大鼠

宿主

  • 93
  • 53
  • 1
  • 1
  • 1
小鼠

克隆类型

  • 82
  • 66
  • 1
单克隆

标记

  • 67
  • 24
  • 12
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This S100A9 antibody is conjugated to CF®568

应用范围

  • 78
  • 56
  • 38
  • 29
  • 28
  • 28
  • 17
  • 14
  • 13
  • 13
  • 9
  • 9
  • 8
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

47-8D3
  • 原理

    Mouse Monoclonal anti-S100A9 (47-8D3), CF568 Conjugate

    产品特性

    This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer's cells of the liver and Langerhan's cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. It plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Human peripheral blood monocyte components

    亚型

    IgG1 kappa
  • 应用备注

    Immunohistology formalin-fixed 0.5-1 μg/mL
    • For staining of formalin-fixed, paraffin-embedded tissues, digest with trypsin at 1 mg/mL PBS, 15 min at RT
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL

    说明

    Liver or histiocytoma

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    S100A9 (S100 Calcium Binding Protein A9 (S100A9))

    别名

    S100A9

    分子量

    14 kDa

    基因ID

    6280, 112405

    UniProt

    P06702

    途径

    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
You are here:
Chat with us!