Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体 (CF®568)
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- 抗原 See all Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) 抗体
- Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)
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抗原表位
- AA 356-475
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- CF®568
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Coating (Coat)
- 原理
- Mouse Monoclonal anti-Spectrin-beta-III (SPTBN2/1582), CF568 Conjugate
- 产品特性
- Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin ? and spectrin ? are present in erythrocytes, whereas spectrin ? II (also designated fodrin ?) and spectrin ? I (also designated fodrin ?) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin ? III is highly homologous to both spectrin ? I and spectrin ? II. Spectrin ? III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- Recombinant human SPTBN2 fragment (aa356-475) (exact sequence is proprietary)
- 克隆位点
- SPTBN2-1582
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product SPTBN2 Primary Antibody
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anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) antibody
SPTBN2 适用: 人, 小鼠, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, FACS, IHC, ELISA, Coat, StM 宿主: 兔 Monoclonal SPTBN2-2894R unconjugated Recombinant Antibody
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal SPTBN2-1583 unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人, 小鼠, 大鼠 WB, FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal SPTBN2-1584 unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, FACS, IF, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal SPTBN2-1582 unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, IF, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal SPTBN2-1778 unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人, 小鼠, 大鼠 WB, IHC, StM 宿主: 兔 Monoclonal SPTBN2-2979R unconjugated Recombinant Antibody
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, FACS, IF, IHC, StM 宿主: 兔 Monoclonal SPTBN2-2887R unconjugated Recombinant Antibody
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, IHC, ELISA, Coat 宿主: 小鼠 Monoclonal rSPTBN2-1778 unconjugated Recombinant Antibody
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 643-720) antibodySPTBN2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D9 unconjugated
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- 应用备注
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Immunohistology (formalin) 0.5-1 μg/mL
- ELISA 2-4 μg/mL for coating (order Ab without BSA)
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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HeLa cells. Pancreas or Liver.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)
- 别名
- Spectrin-beta-III (SPTBN2 产品)
- 别名
- Spnb3 antibody, mKIAA0302 antibody, GTRAP41 antibody, SCA5 antibody, spectrin beta, non-erythrocytic 2 antibody, spectrin, beta, non-erythrocytic 2 antibody, Sptbn2 antibody, SPTBN2 antibody
- 背景
- Beta III spectrin, SCA5, Spectrin beta chain brain 2, Spectrin beta non-erythrocytic 2, Spectrin non-erythroid beta chain 2, Spinocerebellar ataxia 5, SPTBN2
- 分子量
- 246 kDa
- 基因ID
- 6712, 26915
- UniProt
- O15020
- 途径
- Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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