IL-10RA 抗体 (pSer319, pSer323)
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Quick Overview for IL-10RA 抗体 (pSer319, pSer323) (ABIN616045)
抗原
See all IL-10RA (IL10RA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer319, pSer323
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序列
- D-S(p)-G-F-G-S(p)-T
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特异性
- This antibody detects endogenous level of IL-10R subunit alpha protein only when phosphorylated at serine 319 and serine 323.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Affinity-chromatography using epitope-specific peptide
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免疫原
- Peptide sequence around phosphorylation site of Serine 319/Serine 323 derived from Human IL-10R subunit alpha.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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别名
- CDw210a / IL10RA
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背景
- Defects in IL10RA are the cause of inflammatory bowel disease type 28 (IBD28) [MIM:613148]. It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous, it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers, fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints.Synonyms: IL-10R-A, IL10 Receptor alpha, Interleukin-10 receptor alpha chain
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分子量
- 63 kDa
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基因ID
- 3587
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NCBI登录号
- NP_001549
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UniProt
- Q13651
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途径
- Growth Factor Binding
抗原
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