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IL-10RA 抗体 (pSer319, pSer323)

This anti-IL-10RA antibody is a 兔 多克隆 antibody detecting IL-10RA in WB. Suitable for 人.
产品编号 ABIN616045
发货至: 中国

Quick Overview for IL-10RA 抗体 (pSer319, pSer323) (ABIN616045)

抗原

See all IL-10RA (IL10RA) 抗体
IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

适用

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宿主

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克隆类型

  • 76
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  • 1
多克隆

标记

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This IL-10RA antibody is un-conjugated

应用范围

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  • 28
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  • 3
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Western Blotting (WB)
  • 抗原表位

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    pSer319, pSer323

    序列

    D-S(p)-G-F-G-S(p)-T

    特异性

    This antibody detects endogenous level of IL-10R subunit alpha protein only when phosphorylated at serine 319 and serine 323.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Affinity-chromatography using epitope-specific peptide

    免疫原

    Peptide sequence around phosphorylation site of Serine 319/Serine 323 derived from Human IL-10R subunit alpha.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store (in aliquots) at -20 °C.
  • 抗原

    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

    别名

    CDw210a / IL10RA

    背景

    Defects in IL10RA are the cause of inflammatory bowel disease type 28 (IBD28) [MIM:613148]. It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous, it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers, fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints.Synonyms: IL-10R-A, IL10 Receptor alpha, Interleukin-10 receptor alpha chain

    分子量

    63 kDa

    基因ID

    3587

    NCBI登录号

    NP_001549

    UniProt

    Q13651

    途径

    Growth Factor Binding
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