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CCBE1 抗体 (AA 35-406)

This anti-CCBE1 antibody is a 兔 多克隆 antibody detecting CCBE1 in WB 和 IF. Suitable for 人.
产品编号 ABIN616002
发货至: 中国

Quick Overview for CCBE1 抗体 (AA 35-406) (ABIN616002)

抗原

See all CCBE1 抗体
CCBE1 (Collagen and Calcium Binding EGF Domains 1 (CCBE1))

适用

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宿主

  • 19
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克隆类型

  • 21
多克隆

标记

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This CCBE1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 7
    • 4
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    AA 35-406

    特异性

    This antibody detects CCBE1.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein-A chromatography

    免疫原

    Highly pure (>95%) recombinant human ccbe1 (Tyr35-Pro406) derived from Sf9 insect cells

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS, pH 7.2

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    The lyophilized antibody is stable at room temperature for up to 1 month. Following reconstitution antibody can be stored at 2-8 °C for up to two weeks or (in aliquots) at -20 °C for longer.
  • 抗原

    CCBE1 (Collagen and Calcium Binding EGF Domains 1 (CCBE1))

    别名

    CCBE1

    背景

    The lymphatic system comprises a vascular system separate from the cardiovascular system, essential for immune responses, fluid homeostasis and fat absorption. Lymphatic vessels develop in a complex process termed lymphangiogenesis that involves budding, migration and proliferation of lymphatic endothelial progenitor cells. A few genes, such as FLT4, FOXC2 and SOX18, are known to be critically involved in lymph vessel formation in humans. Lymphedema, lymphangiectasias, mental retardation and unusual facial characteristics define the autosomal recessive Hennekam syndrome. Homozygosity mapping identified a critical chromosomal region containing ccbe1, encoding Collagen and Calcium-Binding EGF-domain-1, a secreted protein which is required for embryonic lymphangiogenesis in zebrafish. ccbe1 is not expressed in endothelial cells of lymph vessels, and it may be a component of the extracellular matrix. In zebrafish, ccbe1 expression was observed along the earliest migration routes of endothelial cells that sprout from the posterior cardinal vein and migrate circuitously before developing into lymphatic vessels. ccbe1 might therefore be involved in guidance of these migrating cells.Synonyms: Collagen and calcium-binding EGF domain-containing protein 1, Full of fluid protein homolog, KIAA1983

    基因ID

    147372

    NCBI登录号

    NP_597716

    UniProt

    Q6UXH8
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