DUOX1 抗体 (Internal Region)
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Quick Overview for DUOX1 抗体 (Internal Region) (ABIN615993)
抗原
See all DUOX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- EKFQRSCLHQ TVQ
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特异性
- This antibody is expected to recognise both reported isoforms (NP_059130.2, NP_787954.1) which are identical.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_059130.2 , NP_787954.1. Genename: DUOX1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DUOX1 (Dual Oxidase 1 (DUOX1))
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别名
- Dual Oxidase 1
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背景
- The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene (from EntrezGene).Synonyms: DUOX, DUOX1, LNOX1, Large NOX 1, Long NOX 1, NADPH thyroid oxidase 1, THOX1, Thyroid oxidase 1
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基因ID
- 53905
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NCBI登录号
- NP_059130
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UniProt
- Q9NRD9
抗原
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