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DUOX1 抗体 (Internal Region)

The 山羊 多克隆 anti-DUOX1 antibody (ABIN615993) specifically detects DUOX1 in IHC (p) 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN615993
发货至: 中国
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Quick Overview for DUOX1 抗体 (Internal Region) (ABIN615993)

抗原

See all DUOX1 抗体
DUOX1 (Dual Oxidase 1 (DUOX1))

适用

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宿主

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山羊

克隆类型

  • 6
多克隆

标记

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This DUOX1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Internal Region

    序列

    EKFQRSCLHQ TVQ

    特异性

    This antibody is expected to recognise both reported isoforms (NP_059130.2, NP_787954.1) which are identical.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

    免疫原

    Peptide with sequence from the internal region of the protein sequence according to NP_059130.2 , NP_787954.1. Genename: DUOX1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    DUOX1 (Dual Oxidase 1 (DUOX1))

    别名

    Dual Oxidase 1

    背景

    The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene (from EntrezGene).Synonyms: DUOX, DUOX1, LNOX1, Large NOX 1, Long NOX 1, NADPH thyroid oxidase 1, THOX1, Thyroid oxidase 1

    基因ID

    53905

    NCBI登录号

    NP_059130

    UniProt

    Q9NRD9
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