HSPG 抗体 (CF®488A)
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- 抗原 See all HSPG 抗体
- HSPG (Heparan Sulphate Protoglycans (HSPG))
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适用
- 人, Cow, 小鼠, 鱼, 猴, Pig
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This HSPG antibody is conjugated to CF®488A
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 原理
- Rat Monoclonal anti-Heparan Sulfate Proteoglycan (A7L6), CF488A Conjugate
- 产品特性
- This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment. Primary antibodies are available purified, or with a selection of fluorescent CF ® dyes and other labels. CF ® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF ®405S and CF ®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- Murine EHS laminin preparation
- 克隆位点
- A7L6
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product HSPG Primary Antibody
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anti-Heparan Sulphate Protoglycans (HSPG) (AA 19-144) antibody
HSPG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heparan Sulphate Protoglycans (HSPG) antibodyHSPG 适用: 人, Cow, 小鼠, 大鼠 WB, IHC, IHC (p), IP, ICC, IHC (fro) 宿主: 大鼠 Monoclonal unconjugated
anti-Heparan Sulphate Protoglycans (HSPG) antibody (Biotin)HSPG 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal Biotin
anti-Heparan Sulphate Protoglycans (HSPG) antibody (FITC)HSPG 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Heparan Sulphate Protoglycans (HSPG) antibodyHSPG 适用: 人, Cow, 小鼠, 鱼, 猴, Pig IHC (p), IF, FACS, IHC (f) 宿主: 大鼠 Monoclonal A7L6 unconjugated
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- 应用备注
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Immunohistology formalin-fixed 1-2 μg/mL
- Staining of formalin/paraffin tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- 说明
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Breast carcinomas, squamous cell carcinomas.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- HSPG (Heparan Sulphate Protoglycans (HSPG))
- 别名
- Heparan Sulfate Proteoglycan (HSPG 产品)
- 别名
- CDW44 antibody, CSPG8 antibody, ECMR-III antibody, HCELL antibody, HUTCH-I antibody, IN antibody, LHR antibody, MC56 antibody, MDU2 antibody, MDU3 antibody, MIC4 antibody, Pgp1 antibody, AU023126 antibody, AW121933 antibody, AW146109 antibody, HERMES antibody, Ly-24 antibody, Pgp-1 antibody, CD44A antibody, METAA antibody, RHAMM antibody, CD44 molecule (Indian blood group) antibody, glypican 3 antibody, CD44 antigen antibody, CD44 antibody, GPC3 antibody, Cd44 antibody
- 背景
- Heparan sulfate proteoglycan of basement membrane, HSPG, Hspg2, LG3 peptide, Perlecan, PLC, SJS1
- 分子量
- >400 kDa
- 基因ID
- 3339, 562227
- UniProt
- P98160
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