CXCR6 抗体 (C-Term)
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北京 101111
Quick Overview for CXCR6 抗体 (C-Term) (ABIN615957)
抗原
See all CXCR6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-SEDNSKTFSA SHN
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特异性
- Recognizes CD186 / CXCR6.
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat, Canine (Dog).
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence from the C Terminus of the protein sequence according to NP_006555.1. Genename: CXCR6
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anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (C-Term) antibody
Verified CXCR6 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) antibodyCXCR6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (C-Term) antibodyCXCR6 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (Cytoplasmic Domain) antibodyCXCR6 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 1-342) antibodyCXCR6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (C-Term) antibodyCXCR6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 319-338) antibodyCXCR6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 3-31), (N-Term) antibodyCXCR6 适用: 人 WB 宿主: 兔 Polyclonal RB33271 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (N-Term) antibodyCXCR6 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
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别名
- CD186 / CXCR6
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背景
- Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) require coreceptors to enter and infect target cells. They are dependent upon an interaction between the viral envelope glycoprotein with T cell antigen T4 (CD4) and a G protein coupled receptor (GPCR). HIV1 infection relies upon interaction with a chemokine receptor, usually chemokine (C-C) receptor 5 (CCR5). During progression of the infection, the virus tends to rely upon chemokine (C-X-C) receptor 4 (CXCR4). SIV also utilizes CCR5 in the early stages of infection, but during progression it tends to rely on two orphan GPCR's named chemokine (C-X-C) receptor 6 (Bonzo) and G protein coupled receptor 15 (BOB/GRP15). Bonzo mRNA expression has been localized to lymphoid tissues and activated peripheral blood lymphocytes.Synonyms: BONZO, CDw186, CXC-R6, CXCR-6, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, STRL33, TYMSTR
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基因ID
- 10663
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NCBI登录号
- NP_006555
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UniProt
- O00574
抗原
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