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CD2 抗体 (CF®405S)

This anti-CD2 antibody is a 小鼠 单克隆 antibody detecting CD2 in FACS 和 IF. Suitable for 人, Pig 和 Non-Human Primate.
产品编号 ABIN6158127
发货至: 中国

Quick Overview for CD2 抗体 (CF®405S) (ABIN6158127)

抗原

See all CD2 抗体
CD2

适用

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人, Pig, Non-Human Primate

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD2 antibody is conjugated to CF®405S

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

LFA2-600
  • 原理

    Mouse Monoclonal anti-CD2 (LFA2/600), CF405S Conjugate

    产品特性

    CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human LFA2 protein

    亚型

    IgG1 kappa
  • 应用备注

    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user

    说明

    293T or Jurkat cells. Lymph node and tonsil

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    CD2

    别名

    CD2

    背景

    Erythrocyte receptor, LFA-2, LFA-3 receptor, Ly-37, Lymphocyte function antigen 2, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, T11

    分子量

    ~50 kDa

    基因ID

    914, 523500

    UniProt

    P06729
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