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CARD11 抗体

CARD11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN615803
发货至: 中国
  • 抗原 See all CARD11 抗体
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    适用
    • 34
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    宿主
    • 32
    • 1
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    克隆类型
    • 34
    • 1
    多克隆
    标记
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CARD11 antibody is un-conjugated
    应用范围
    • 27
    • 11
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    • 6
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    • 3
    • 2
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody reacts to Caspase Recruitment Domain Family, Member 11 (CARD11). Predicted cross-reactivity based on amino acid sequence homology: mouse (96 %), bovine (98 %).
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    CARD11 antibody was raised against recombinant protein Genename: CARD11
    Top Product
    Discover our top product CARD11 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1,02 mg/mL
    缓冲液
    0.1 M Tris-glycine, pH 7.0 containing 10 % Glycerol as stabilizer and 0.01 % Thimerosal as preservative
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    别名
    CARD11 / CARMA1 (CARD11 产品)
    别名
    BENTA antibody, BIMP3 antibody, CARMA1 antibody, PPBL antibody, 0610008L17Rik antibody, 2410011D02Rik antibody, CARD11 antibody, LOC100232755 antibody, caspase recruitment domain family member 11 antibody, caspase recruitment domain family, member 11 antibody, caspase recruitment domain-containing protein 11 antibody, CARD11 antibody, Card11 antibody, LOC100550812 antibody, card11 antibody
    背景
    CARMA proteins belong to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. Both CARMA1 and CARMA3 associate with NEMO, the regulatory subunit of the IkK complex, thereby regulating activation of the NF-kB transcription factor. Also, gene inactivation studies showed a complete block in T and B cell immunity as well as an impaired response to LPS, indicating that CARMA1 is a critical regulator in both the adaptive and innate immune systems.Synonyms: CARD-containing MAGUK protein 3, Caspase recruitment domain-containing protein 11
    基因ID
    84433
    NCBI登录号
    NP_115791
    UniProt
    Q9BXL7
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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