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AMPD3 抗体 (CF®405S)

This anti-AMPD3 antibody is a 小鼠 单克隆 antibody detecting AMPD3 in IF, ICC, FACS 和 IHC (f). Suitable for 人.
产品编号 ABIN6155505
发货至: 中国

Quick Overview for AMPD3 抗体 (CF®405S) (ABIN6155505)

抗原

See all AMPD3 抗体
AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This AMPD3 antibody is conjugated to CF®405S

应用范围

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Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

AMPD3-901
  • 原理

    Mouse Monoclonal anti-Adenosine Monophosphate Deaminase-3 (AMPD3) (AMPD3/901), CF405S Conjugate

    产品特性

    This antibody recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human AMDP3 protein

    亚型

    IgG2b kappa
  • 应用备注

    Immunohistology formalin-fixed 2-4 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Immunocytochemistry 1-2.0 μg/mL
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 1-2 μg/million cells in 0.1 mL
    • Optimal dilution for a specific application should be determined by user

    说明

    RBC. Fetal liver, Spleen or Placenta

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

    别名

    Adenosine Monophosphate Deaminase-3 (AMPD3)

    分子量

    90 kDa

    基因ID

    272, 501890

    UniProt

    Q01432
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