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MHC, Class I 抗体 (CF®640R)

The CF®640R-conjugated 小鼠 单克隆 anti-MHC, Class I antibody (Clone 246-B8-E7) (ABIN6155357) specifically detects MHC, Class I in FACS 和 IF. The antibody is reactive with 小鼠, 人 和 Non-Human Primate samples.
产品编号 ABIN6155357
发货至: 中国
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中国
北京 101111
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Room 801-803
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Quick Overview for MHC, Class I 抗体 (CF®640R) (ABIN6155357)

抗原

See all MHC, Class I 抗体
MHC, Class I

适用

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  • 1
小鼠, 人, Non-Human Primate

宿主

  • 66
  • 58
  • 9
  • 1
小鼠

克隆类型

  • 95
  • 36
  • 3
单克隆

标记

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This MHC, Class I antibody is conjugated to CF®640R

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

246-B8-E7
  • 原理

    Mouse Monoclonal anti-MHC-I (246-B8.E7), CF640R Conjugate

    产品特性

    This antibody recognizes a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Human peripheral blood leukocytes

    亚型

    IgG2a kappa
  • 应用备注

    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user

    说明

    THP-1 and Jurkat cells. Tonsil or lymph node.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    MHC, Class I

    别名

    MHC-I

    背景

    HLA-A, HLA-B, HLA-C, HLA class 1A, HLA class 1B, HLA class 1C, Major histocompatibility complex, class I, A B C, MHC class I HLA-A, MHC class I HLA-B, MHC class I HLA-C, MHC HLA-ABC

    分子量

    ~41 kDa

    基因ID

    3105, 181244, 654404

    UniProt

    P01889, P30443, P30499
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