VWF 抗体 (AA 1815-1939) (CF®647)
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Quick Overview for VWF 抗体 (AA 1815-1939) (CF®647) (ABIN6154639)
抗原
See all VWF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1815-1939
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原理
- Mouse Monoclonal anti-von-Willebrand Factor / Factor-VIII-Related Ag (VWF/1767), CF647 Conjugate
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产品特性
- von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment of human vWF protein (aa1815-1939) (exact sequence is proprietary)
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亚型
- IgG2b kappa
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anti-Von Willebrand Factor (VWF) (AA 1498-1665) antibody
VWF 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 269-367) antibodyVWF 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 50-150) antibodyVWF 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1815-1939) antibodyVWF 适用: 人 IHC, WB, StM 宿主: 小鼠 Monoclonal VWF-1465 unconjugated
anti-Von Willebrand Factor (VWF) (AA 1304-1452) antibodyVWF 适用: 大鼠, 小鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 2535-2813) antibodyVWF 适用: 人 IHC, WB, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) antibodyVWF 适用: 人 IHC, WB, FACS, ELISA 宿主: 小鼠 Monoclonal 907CT12-1-9 unconjugated
anti-Von Willebrand Factor (VWF) (AA 351-450) antibodyVWF 适用: 人, 大鼠, 小鼠 FACS, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 49-230) antibodyVWF 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1815-1939) antibodyVWF 适用: 人 IHC 宿主: 兔 Monoclonal 521R unconjugated Recombinant Antibody
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应用备注
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Immunohistology (formalin) 1-2 μg/mL
- ELISA 2-4 μg/mL for coating (order Ab without BSA)
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
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说明
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HUVEC cells or Tonsil
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- VWF (Von Willebrand Factor (VWF))
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别名
- von-Willebrand Factor / Factor-VIII-Related Ag
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背景
- Coagulation Factor VIII, Factor VIII Related Antigen, F8VWF, von Willebr, Antigen 2, von Willebr, Disease (vWD)
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分子量
- 250 kDa
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基因ID
- 7450, 440848
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UniProt
- P04275
抗原
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