TAG-72 / CA72.4 抗体 (CF®488A)
Quick Overview for TAG-72 / CA72.4 抗体 (CF®488A) (ABIN6153855)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-TAG-72 / CA72.4 (B72.3 + CA72/733), CF488A Conjugate
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产品特性
- This antibody recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. See the < a href="https://biotium.com/wp-content/uploads/2013/07/CF-dye-selection-guide.pdf" target="_blank" rel="noopener">CF® Dye Selection Guide for more information. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- TAG-72 protein (B72.3 & CA72/733)
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亚型
- IgG
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anti-TAG-72 / CA72.4 antibody
适用: 人, 犬, Cow, 大鼠, Hamster FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal B72-3 unconjugated
anti-TAG-72 / CA72.4 antibody适用: 人, 犬, Cow, 大鼠, Hamster IHC, StM 宿主: 兔 Monoclonal CA72-2869R unconjugated Recombinant Antibody
anti-TAG-72 / CA72.4 antibody适用: 人, 犬, Cow, 大鼠, Hamster IHC, StM 宿主: 小鼠 Monoclonal rB72-3 unconjugated Recombinant Antibody
anti-TAG-72 / CA72.4 antibody适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal CA72-145 unconjugated
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应用备注
- Flow Cytometry 0.5-1 μg/million cells/0.1 mLImmunofluorescence 1-2 μg/mL
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说明
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Jurkat cells, Breast or lung carcinoma.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- TAG-72 / CA72.4
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背景
- CA72.4, Tumor associated glycoprotein 72
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分子量
- 220 kDa
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基因ID
- 182875
抗原
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