HLA-DP beta 抗体 (CF®568)
This anti-HLA-DP beta antibody is a 小鼠 单克隆 antibody detecting HLA-DP beta in FACS, IF 和 IHC (f). Suitable for 人.
Quick Overview for HLA-DP beta 抗体 (CF®568) (ABIN6153353)
抗原
HLA-DP beta
(MHC Class II HLA-DP beta (HLA-DP beta))
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This HLA-DP beta antibody is conjugated to CF®568
应用范围
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
克隆位点
Bra-14
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原理
- Mouse Monoclonal anti-MHC-II (HLA-DP beta chain) (Bra-14), CF568 Conjugate
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产品特性
- This antibody recognizes a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Human REH cells
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亚型
- IgG3 kappa
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anti-MHC Class II HLA-DP beta (HLA-DP beta) antibody
HLA-DP beta 适用: 人 FACS, IF, IHC (f) 宿主: 小鼠 Monoclonal Bra-14 unconjugated
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应用备注
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Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
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说明
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Raji cells. Tonsil or lymph node
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- HLA-DP beta (MHC Class II HLA-DP beta (HLA-DP beta))
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别名
- MHC-II (HLA-DP) (beta chain)
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分子量
- 36 kDa (? chain) and 27 kDa (? chain)
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基因ID
- 3115, 3122
抗原
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