S100A8/A9 Complex (Calprotectin) 抗体 (CF®594)
Quick Overview for S100A8/A9 Complex (Calprotectin) 抗体 (CF®594) (ABIN6152299)
抗原
See all S100A8/A9 Complex (Calprotectin) (S100A8/A9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-Calgranulin-B / MRP-8/-14 / MAC-387 / S100A8/A9 / Macrophage Ag (MAC387), CF594 Conjugate
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产品特性
- This antibody recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12 kDa alpha chain and a 14 kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupffer's cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi and helminthes. This MAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Affinity purified monocyte membrane preparation
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亚型
- IgG1 kappa
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anti-Calprotectin (S100A8/A9) antibody
S100A8/A9 适用: 人, Pig, Cow, Cat, 犬, 豚鼠, 猴, 兔, 大鼠, 小鼠, 马, Baboon, 山羊 IHC, StM 宿主: 小鼠 Monoclonal rMAC3781 unconjugated Recombinant Antibody
anti-Calprotectin (S100A8/A9) antibodyS100A8/A9 适用: 人, Pig, Cow, Cat, 犬, 豚鼠, 猴, 兔, 大鼠, 小鼠, 马, Baboon, 山羊 IHC, StM 宿主: 兔 Monoclonal MAC3157R unconjugated Recombinant Antibody
anti-Calprotectin (S100A8/A9) (AA 1-114) antibodyS100A8/A9 适用: 人 IHC, WB, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Calprotectin (S100A8/A9) antibodyAnimal-Free S100A8/A9 适用: 人 ELISA 宿主: 小鼠 Monoclonal AB467-1-A05 unconjugated Recombinant Antibody
anti-Calprotectin (S100A8/A9) antibodyS100A8/A9 适用: 人 IHC, WB, ELISA 宿主: 小鼠 Monoclonal 69-6-1 unconjugated
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应用备注
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Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
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说明
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Tonsil, lymph node, or spleen
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- S100A8/A9 Complex (Calprotectin) (S100A8/A9) (Calprotectin (S100A8/A9))
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别名
- Calgranulin-B / MRP-8/-14 / MAC-387 / S100A8/A9 / Macrophage Ag
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分子量
- 12-14 kDa (doublet)
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基因ID
- 6279, 6280
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途径
- S100 Proteins
抗原
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