UMPS
适用: 人, 小鼠, 大鼠
IF
宿主: 兔
Polyclonal
unconjugated
应用备注
WB,1:500 - 1:2000,IF,1:50 - 1:100
限制
仅限研究用
状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
UMPS
(Uridine Monophosphate Synthetase (UMPS))
别名
UMPS
背景
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.,UMPS,OPRT,Epigenetics & Nuclear Signaling,Endocrine & Metabolism,Nucleotide metabolism,Purine and pyrimidine synthesis,UMPS