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UBL4A 抗体 (AA 1-157)

UBL4A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6149851
发货至: 中国
  • 抗原 See all UBL4A 抗体
    UBL4A (Ubiquitin-Like 4A (UBL4A))
    抗原表位
    • 8
    • 2
    • 1
    • 1
    • 1
    AA 1-157
    适用
    • 26
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 20
    • 6
    克隆类型
    • 22
    • 4
    多克隆
    标记
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBL4A antibody is un-conjugated
    应用范围
    • 14
    • 8
    • 6
    • 5
    • 2
    Western Blotting (WB), Immunoprecipitation (IP)
    序列
    MQLTVKALQG RECSLQVPED ELVSTLKQLV SEKLNVPVRQ QRLLFKGKAL ADGKRLSDYS IGPNSKLNLV VKPLEKVLLE EGEAQRLADS PPPQVWQLIS KVLARHFSAA DASRVLEQLQ RDYERSLSRL TLDDIERLAS RFLHPEVTET MEKGFSK
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-157 of human UBL4A (NP_055050.1).
    亚型
    IgG
    Top Product
    Discover our top product UBL4A Primary Antibody
  • 应用备注
    WB,1:200 - 1:1000,IP,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    UBL4A (Ubiquitin-Like 4A (UBL4A))
    别名
    UBL4A (UBL4A 产品)
    别名
    DX254E antibody, DXS254E antibody, G6PD antibody, GDX antibody, GET5 antibody, MDY2 antibody, TMA24 antibody, UBL4 antibody, DXHXS254E antibody, DXS254Eh antibody, Gdx antibody, Ubl4a antibody, MGC128599 antibody, gdx antibody, g6pd antibody, ubl4 antibody, dx254e antibody, dxs254e antibody, RGD1563983 antibody, Ubl4 antibody, ubl4a antibody, Slc10a3 antibody, ubiquitin like 4A antibody, ubiquitin-like 4A antibody, ubiquitin like 4A S homeolog antibody, zgc:56596 antibody, ubiquitin-like protein 4A antibody, UBL4A antibody, Ubl4a antibody, ubl4a antibody, ubl4a.S antibody, zgc:56596 antibody, LOC100723318 antibody
    背景
    As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum. Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome. Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum. The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD, a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome.,UBL4A,DX254E,DXS254E,G6PD,GDX,GET5,MDY2,TMA24,UBL4,Cell Biology & Developmental Biology,Ubiquitin,UBL4A
    分子量
    17 kDa
    基因ID
    8266
    UniProt
    P11441
    途径
    Ubiquitin Proteasome Pathway
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