UBL4A 抗体 (AA 1-157)
Quick Overview for UBL4A 抗体 (AA 1-157) (ABIN6149851)
抗原
See all UBL4A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-157
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序列
- MQLTVKALQG RECSLQVPED ELVSTLKQLV SEKLNVPVRQ QRLLFKGKAL ADGKRLSDYS IGPNSKLNLV VKPLEKVLLE EGEAQRLADS PPPQVWQLIS KVLARHFSAA DASRVLEQLQ RDYERSLSRL TLDDIERLAS RFLHPEVTET MEKGFSK
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-157 of human UBL4A (NP_055050.1).
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亚型
- IgG
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anti-Ubiquitin-Like 4A (UBL4A) (AA 1-157) antibody
UBL4A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin-Like 4A (UBL4A) antibodyUBL4A 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D4 unconjugated
anti-Ubiquitin-Like 4A (UBL4A) antibodyUBL4A 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like 4A (UBL4A) (AA 1-157) antibodyUBL4A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C10 unconjugated
anti-Ubiquitin-Like 4A (UBL4A) antibodyUBL4A 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-Ubiquitin-Like 4A (UBL4A) antibodyUBL4A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like 4A (UBL4A) (C-Term) antibodyUBL4A 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like 4A (UBL4A) (AA 81-130) antibodyUBL4A 适用: 人, 大鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like 4A (UBL4A) (C-Term) antibodyUBL4A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:200 - 1:1000,IP,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- UBL4A (Ubiquitin-Like 4A (UBL4A))
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别名
- UBL4A
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背景
- As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum. Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome. Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum. The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD, a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome.,UBL4A,DX254E,DXS254E,G6PD,GDX,GET5,MDY2,TMA24,UBL4,Cell Biology & Developmental Biology,Ubiquitin,UBL4A
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分子量
- 17 kDa
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基因ID
- 8266
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UniProt
- P11441
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途径
- Ubiquitin Proteasome Pathway
抗原
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