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TXNIP 抗体 (AA 1-166)

This anti-TXNIP antibody is a 兔 多克隆 antibody detecting TXNIP in WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6149733
发货至: 中国

Quick Overview for TXNIP 抗体 (AA 1-166) (ABIN6149733)

抗原

See all TXNIP 抗体
TXNIP (Thioredoxin Interacting Protein (TXNIP))

适用

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宿主

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克隆类型

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多克隆

标记

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This TXNIP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-166

    序列

    MVMFKKIKSF EVVFNDPEKV YGSGEKVAGR VIVEVCEVTR VKAVRILACG VAKVLWMQGS QQCKQTSEYL RYEDTLLLED QPTGENEMVI MRPGNKYEYK FGFELPQGPL GTSFKGKYGC VDYWVKAFLD RPSQPTQETK KNFEVVDLVD VNTPDLMAPV SAKKEK

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human TXNIP (NP_006463.3).

    亚型

    IgG
  • 应用备注

    WB,1:200 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhang, Zhang, Deng, Zhang, Xu: "Baicalin protects AML-12 cells from lipotoxicity via the suppression of ER stress and TXNIP/NLRP3 inflammasome activation." in: Chemico-biological interactions, Vol. 278, pp. 189-196, (2017) (PubMed).

  • 抗原

    TXNIP (Thioredoxin Interacting Protein (TXNIP))

    别名

    TXNIP

    背景

    This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.,TXNIP,ARRDC6,EST01027,HHCPA78,THIF,VDUP1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Carbohydrate metabolism,TXNIP

    分子量

    37 kDa/43 kDa

    基因ID

    10628

    UniProt

    Q9H3M7

    途径

    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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