TRIB2 抗体 (AA 1-120)
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北京 101111
Quick Overview for TRIB2 抗体 (AA 1-120) (ABIN6149496)
抗原
See all TRIB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-120
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序列
- MNIHRSTPIT IARYGRSRNK TQDFEELSSI RSAEPSQSFS PNLGSPSPPE TPNLSHCVSC IGKYLLLEPL EGDHVFRAVH LHSGEELVCK VFDISCYQES LAPCFCLSAH SNINQITEII
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human TRIB2 (NP_067675.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
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别名
- TRIB2
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背景
- This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.,TRIB2,C5FW,GS3955,TRB2,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,Immunology & Inflammation,Stem Cells,Hematopoietic Progenitors,Cardiovascular,TRIB2
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分子量
- 38 kDa
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基因ID
- 28951
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UniProt
- Q92519
抗原
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