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CARD11 抗体 (C-Term)

CARD11 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN614918
发货至: 中国
  • 抗原 See all CARD11 抗体
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    抗原表位
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 34
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 32
    • 1
    • 1
    • 1
    山羊
    克隆类型
    • 34
    • 1
    多克隆
    标记
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CARD11 antibody is un-conjugated
    应用范围
    • 27
    • 11
    • 10
    • 9
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    C-QRKTIWVDED QL
    特异性
    This antibody detects CARD11 / CARMA1 at C-term.
    交叉反应 (详细)
    Species reactivity (expected):MouseSpecies reactivity (tested):Human
    纯化方法
    Immunoaffinity chromatography
    免疫原
    Synthetic peptide from C-term of human CARD11 Genename: CARD11
    Top Product
    Discover our top product CARD11 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline buffer, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    别名
    CARD11 / CARMA1 (CARD11 产品)
    别名
    BENTA antibody, BIMP3 antibody, CARMA1 antibody, PPBL antibody, 0610008L17Rik antibody, 2410011D02Rik antibody, CARD11 antibody, LOC100232755 antibody, caspase recruitment domain family member 11 antibody, caspase recruitment domain family, member 11 antibody, caspase recruitment domain-containing protein 11 antibody, CARD11 antibody, Card11 antibody, LOC100550812 antibody, card11 antibody
    背景
    CARMA proteins belong to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. Both CARMA1 and CARMA3 associate with NEMO, the regulatory subunit of the IkK complex, thereby regulating activation of the NF-kB transcription factor. Also, gene inactivation studies showed a complete block in T and B cell immunity as well as an impaired response to LPS, indicating that CARMA1 is a critical regulator in both the adaptive and innate immune systems.Synonyms: CARD-containing MAGUK protein 3, Caspase recruitment domain-containing protein 11
    基因ID
    84433
    NCBI登录号
    NP_115791
    UniProt
    Q9BXL7
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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