CARD11 抗体 (C-Term)
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Quick Overview for CARD11 抗体 (C-Term) (ABIN614918)
抗原
See all CARD11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-QRKTIWVDED QL
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特异性
- This antibody detects CARD11 / CARMA1 at C-term.
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交叉反应 （详细）
- Species reactivity (expected):MouseSpecies reactivity (tested):Human
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纯化方法
- Immunoaffinity chromatography
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免疫原
- Synthetic peptide from C-term of human CARD11 Genename: CARD11
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anti-Caspase Recruitment Domain Family, Member 11 (CARD11) antibody
CARD11 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (C-Term) antibodyVerified CARD11 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (Internal Region) antibodyCARD11 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (AA 985-1154) antibodyCARD11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) antibodyCARD11 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1990 unconjugated Recombinant Antibody
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (N-Term) antibodyCARD11 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (N-Term) antibodyCARD11 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (AA 481-580) antibodyCARD11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (N-Term) antibodyCARD11 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (AA 985-1154) antibodyCARD11 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline buffer, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
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别名
- CARD11 / CARMA1
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背景
- CARMA proteins belong to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. Both CARMA1 and CARMA3 associate with NEMO, the regulatory subunit of the IkK complex, thereby regulating activation of the NF-kB transcription factor. Also, gene inactivation studies showed a complete block in T and B cell immunity as well as an impaired response to LPS, indicating that CARMA1 is a critical regulator in both the adaptive and innate immune systems.Synonyms: CARD-containing MAGUK protein 3, Caspase recruitment domain-containing protein 11
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基因ID
- 84433
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NCBI登录号
- NP_115791
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UniProt
- Q9BXL7
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
抗原
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