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SPTAN1 抗体 (AA 950-1130)

This anti-SPTAN1 antibody is a 兔 多克隆 antibody detecting SPTAN1 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6148403
发货至: 中国

Quick Overview for SPTAN1 抗体 (AA 950-1130) (ABIN6148403)

抗原

See all SPTAN1 抗体
SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

适用

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宿主

  • 128
  • 36
  • 1

克隆类型

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多克隆

标记

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This SPTAN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 950-1130

    序列

    REQAQSCRQQ VAPTDDETGK ELVLALYDYQ EKSPREVTMK KGDILTLLNS TNKDWWKVEV NDRQGFVPAA YVKKLDPAQS ASRENLLEEQ GSIALRQEQI DNQTRITKEA GSVSLRMKQV EELYHSLLEL GEKRKGMLEK SCKKFMLFRE ANELQQWINE KEAALTSEEV GADLEQVEVL Q

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 950-1130 of human Alpha Fodrin (NP_001123910.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Meng, Zhang, Shi, Zhang, Yuan: "Inhibition of interleukin-6 abolishes the promoting effects of pair housing on post-stroke neurogenesis." in: Neuroscience, Vol. 307, pp. 160-70, (2016) (PubMed).

  • 抗原

    SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

    别名

    SPTAN1

    背景

    Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.,SPTAN1,EIEE5,NEAS,SPTA2,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Microfilaments,Death Receptor Signaling Pathway,SPTAN1

    分子量

    282 kDa/284 kDa/285 kDa

    基因ID

    6709

    UniProt

    Q13813

    途径

    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization
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