SNX13 抗体 (AA 50-230)
Quick Overview for SNX13 抗体 (AA 50-230) (ABIN6148236)
抗原
See all SNX13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-230
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序列
- FGKTNSEKYL EQCEHSFLPP TSPGVPKCLE EMKREARTIK IDRRLTGANI IDEPLQQVIQ FSLRDYVQYW YYTLSDDESF LLEIRQTLQN ALIQFATRSK EIDWQPYFTT RIVDDFGTHL RVFRKAQQKI TEKDDQVKGT AEDLVDTFFE VEVEMEKEVC RDLVCTSPKD EEGFLRDLCE V
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 50-230 of human SNX13 (NP_055947.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SNX13 (Sorting Nexin 13 (SNX13))
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别名
- SNX13
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背景
- This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.,SNX13,RGS-PX1,Signal Transduction,G protein signaling,SNX13
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分子量
- 110 kDa/112 kDa
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基因ID
- 23161
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UniProt
- Q9Y5W8
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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